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Given the limited therapeutic benefits associated with NAC in cancer treatment, and the number of other antioxidants shown above to help reduce the toxicities of these two chemotherapeutic agents, there appears little reason to consider NAC a first-line adjunct with either agent

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If you choose to combine them, starting with lower concentrations of each makes sense until you understand how your scalp responds

et al., Targeted apoptosis of senescent cells restores tissue homeostasis in response to chemotoxicity and aging. Cell , 2017