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3.4.3 Mechanistic insights from preclinical modelsbarrier, immune, and neurotransmitter changes Rodent models of PTSD provide causal evidence that psychological trauma disrupts the MGBA, leading to microbiota alterations, compromised gut barrier integrity, immune activation and neurotransmitter imbalance

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Large clinical trials have not consistently shown that isolated antioxidant supplements prevent cardiovascular disease in generally well-nourished populations

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The separation via HPLC follows an isocratic method at 30 C using a reversed-phase column in two runs