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10.1016/j.ejphar.2020.173473 149 ShimadaK.SkoutaR.KaplanA.YangW

Many people spend months applying different creams and products, only to watch the rash worsen

Functional enrichment indicated strong activation of iron transport and lipid peroxidation pathways, but weak engagement of glutathione metabolism, suggesting selective vulnerability to iron-driven oxidative stress

Unlike natural IGF-1, IGF-1 LR3 has been structurally modified to reduce binding to IGF-binding proteins, which allows it to remain active longer in experimental models