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Description

As oligodendrocytes are the main sites of iron storage in the brain 24 , the stimulation of FPN1-mediated iron export via decreased hepcidin is expected to increase free extracellular iron, which may, in turn, result in oxidative stress in the SN in PD patients

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Examining the reasons for the disparity may help to identify some issues that are not being discussed and addressed with patients

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Gut (2006) 55(6):88693

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