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Yes, maintaining a calorie deficit is key

Taking the injection before bed allows you to sleep through the peak of initial nausea, which typically occurs 6 to 12 hours after administration

Vehicle-treated MC4R KO mice showed significantly increased food intake compared with that of wild-type mice throughout the study

Report suspected side effects through the MHRA Yellow Card scheme and seek medical review if anxiety symptoms are severe, persistent, or accompanied by thoughts of self-harm