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For the full picture on each medication, see microdosing tirzepatide and microdosing semaglutide

A useful benchmark: if you have lost 20 percent or more of starting body weight, if your appetite is well-controlled, and if you are tolerating the current dose without significant GI burden, there is no clinical imperative to escalate further

Adjust portions up or down based on your body weight, activity level, and how your appetite responds to your specific semaglutide dosage or tirzepatide dosage

Mazdutide, a dual glucagon and GLP-1 agonist, is approved

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