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The bidirectional communication between the gut, brain, and kidneys suggests that stress-induced changes in gut microbiota, inflammatory processes, and neural pathways can directly influence kidney function

THE TARGET CONCENTRATION APPROACH TO DESIGNING A RATIONAL DOSAGE REGIMEN A rational dosage regimen is based on the assumption that there is a target concentration that will produce the desired therapeutic effect

The enzyme tyrosinase drives this process, and glutathione interferes with it in two important ways

Reduce dose by 3040% and titrate upward over 710 days

In: Rizvi S and akatay U (eds) Molecular Basis and Emerging Strategies for Anti-aging Interventions, Springer, Singapore, pp 253265

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