One study showed that overweight or obese patients taking semaglutide lost nearly 6% of their body weight after 3 months, nearly 11% after 6 months, and a total of 15% of weight loss after 2 years
These drugs are whats known as GLP-1s, just like Ozempic, the popular diabetes medication that kicked off a revolution in the pharmaceutical industry and inspired as many as 12% of people in the U.S
Regardless, these are all resolved quite quickly in most people
GLP-1 receptor agonists work through several mechanisms: they enhance insulin secretion when blood glucose levels are elevated, suppress glucagon release (which reduces glucose production by the liver), slow gastric emptying, and promote satiety through effects on appetite centres in the brain
Similarly, in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced PD mouse model, GLP-1 analogues were reported to protect the brain from MPTP-induced pathological effects, such as movement disorders, increased levels of -synuclein, chronic inflammation in the brain, loss of dopaminergic neurons, oxidative stress, and expression of growth factors (65)
Digestion is already slowed by the medication
