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For a drug producing nearly 30% weight loss, an 11.3% discontinuation rate is the kind of trade-off most patients and most clinicians will accept

It still required smart eating, exercise, and consistency

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Semaglutide, a glucagon-like peptiede-1 (GLP-1) receptor agonist, was approved by the Food and Drug Administration (FDA) to treat diabetes in 2017 and for weight loss in 2021 [3]

Most Effective FDA-Approved Weight Loss Medication Available The SURMOUNT-1 trial's 22.5% average weight reduction at 15mg is the highest ever documented in a randomized controlled weight loss trial surpassing semaglutide and approaching bariatric surgical outcomes

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