Fine line and wrinkle reduction occurs through multiple mechanisms, including increased dermal volume from enhanced collagen production, improved skin hydration, and better cellular organization
Chen Y, Yan W, Chen Y, Zhu J, Wang J, Jin H, et al
The adverse reactions included both temporary exacerbations similar to the "Jarisch Herxheimer reaction" and non-Herxheimer reactions
Materials and methods Antibodies Polyclonal IGF-1R antibody, mouse monoclonal Cre antibody, and mouse glutamine synthetase antibodies suitable for immunohistochemistry were purchased from Abcam (Cambridge, MA)
There is bipartisan support for this legislation, and with the increasing recognition of obesity as a disease, we may see changes in the near future
The study's single-blind design and placebo control add credibility, but the very small sample size means the results should be interpreted cautiously