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[85] Healthcare providers should consider alternative therapeutic approaches, including non-pharmacological interventions, when treating depression in pregnant women, particularly during the first trimester when organogenesis occurs

This change is considered to result in lower extracellular GABA levels and the disruption of E/I balance toward predominately excitatory transmission, which was observed in another study that employed a rat model of prenatal VPA exposure (111)

Upon analyzing the blood samples collected from these subjects, it was observed that there appeared to be a concentration-dependent increase, of up to 10 times, in the concentration of growth hormones among the peptide subjects

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Although these lesions can also occur spontaneously in different rodents with different diseases or with certain neoplasms causing hemodynamic changes, it can also be induced by different compounds