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Below age 18, insufficient safety and efficacy data exist for regulatory approval

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Using a scale from 0 to 4, the following parameters were applied to measure macroscopic harm based on clinical signs and standardized to all animals in the study: 0, the absence of macroscopic abnormalities

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This non-response phenomenonsometimes called treatment resistanceisn't a sign of failure but rather evidence that weight loss biology is deeply individual

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Additionally, six normal mice served as controls

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