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So we need to get that weight loss in the range of, in many patients, in the range of 15% or so, to address the obesity-related complications

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Methods: Male C57BL/6J mice were randomly assigned to six groups: normal control, model, low-dose MOS (12.5 mg/kg), medium-dose MOS (25 mg/kg), high-dose MOS (50 mg/kg), and positive control (L-carnitine 10 mg/kg)

The risks of sustained GH and IGF-1 elevation mirror mild acromegaly-like effects