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N Engl J Med 345(12):851860 Brenner BM, Cooper ME, de Zeeuw D, Keane WF, Mitch WE, Parving H-H et al (2001Effects) Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy

Int J Radiat Oncol Biol Phys 18:10691075

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Biomarker assessmentincluding baseline GLP-1 levels, insulin sensitivity, lipid metabolism markers, and genetic predispositionsmay help providers tailor initial expectations and dosing strategies

The dosages may be adjusted over time, and the patients response to the medication is closely monitored to achieve the best possible outcomes, with the goal of reaching a maintenance dose that supports long-term weight management success