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Morales DK, Grahl N, Okegbe C, Dietrich LE, Jacobs NJ, Hogan DA

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For example, protein preloads [57] or large quantities of single amino acids (glutamine) [58] have been used to elicit higher GLP-1 responses by enhancing GLP-1 secretion

These early immunotherapies were non-specific, however within the past decade the utilization of targeted immunotherapies have risen with monoclonal antibodies that block immune checkpoint molecules, such as cytotoxic T-lymphocyte associated protein4 (CTLA-4), programmed cell death protein-1 (PD-1), and programmed death ligand-1 (PD-L1), adoptive T-cell therapies and oncolytic viruses (151, 153155)

776 Haukka, J