If you are curious about how semaglutide compares to other compounds sometimes discussed in similar regulatory contexts, the breakdown of semaglutide vs tirzepatide is worth reading
Yes, it is possible to do the trek without a guide, as it doesnt require an official permit like the Inca Trail
doi:10.1097/00000441-200609000-00004 Gyftaki H, Kesse-Elias M, Koutras D, Pandos P, Papazoglou S, Moulopoulos S
GLP-1 reduces appetite and slows stomach emptying
1 INDICATIONS AND USAGE INDICATIONS & USAGE SECTION WEGOVY injection is indicated in combination with a reduced calorie diet and increased physical activity: to reduce the risk of major adverse cardiovascular (CV) events (CV death, non-fatal myocardial infarction, or non-fatal stroke) in adults with established CV disease and either obesity or overweight
Before anyone noticed the pounds dropping, researchers were tracking hemoglobin A1C levels , and the results were impressive enough to earn FDA approval in 2017