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It is FDA-approved specifically for HIV-associated lipodystrophy and is not approved for general weight loss

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Aziz, A

Jorsal A, Kistorp C, Holmager P, Tougaard RS, Nielsen R, Hnselmann A, et al

Furthermore, we identify associations linking variation in both GLP1R and GIPR to GLP1 medication-related nausea or vomiting, with the GIPR association being restricted to people using tirzepatide