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doi: 10.1016/j.cca.2020.05.041 58 SansgiryS

Secondary endpoints included the proportion of participants achieving 5% and 10% body weight reduction, absolute weight change in kg, change in waist circumference, lipid parameters including total cholesterol, HDL, LDL, VLDL, triglycerides, and glycaemic variables such as HbA1c, fasting glucose, insulin, HOMA-IR, and -cell function

Are there any side effects or risks associated with the therapy

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Griffith, R

This application requires careful medical supervision given limited human data, though gene expression profiles showing 408 neuronal genes upregulated suggest potential for cognitive enhancement protocols