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Studies continue to investigate GHK-Cu's wide-ranging effects on gene expression, with over 4,000 human genes identified as being modulated by this peptide
These processes contribute to impaired microcirculation and elevated cardiovascular risk in CKD
125 Future research should be directed toward translating animal model findings into early-phase human trials to target and individualize the management of ABC transporter-associated cholestatic disease
VD deficiency results in neuronal cell death by inducing neuroexcitatory toxicity via triggering a sudden increase in cytoplasmic Ca 2+ , elevating ROS generation, and inducing mitochondrial dysfunction
10.1016/j.biopha.2021.111661 328 MiyakeS.KimS.SudaW.OshimaK.NakamuraM.MatsuokaT.et al