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After incubation of fibroblasts with 500 microM of OHCbl, a 75% decrease of intracellular cyanide was observed, with concomittant formation of intracellular cyanocobalamin CNCbl (intracellular/extracellular ratio: 158)
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A., & Ukkola, O
Hypokalemia and thrombocytosis could occur upon conversion of severe megaloblastic anemia to normal erythropoiesis with methylcobalamin therapy
(Explains that compounded medications under Section 503A are exempt from FDA pre-market approval requirements, meaning their safety and efficacy are not evaluated by FDA prior to use)
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