Eye Health Concerns Emerging research suggests a possible link between GLP-1 use and neovascular age-related macular degeneration (AMD), a leading cause of blindness
Some people have loss of appetite or other mild problems with digestion from Trulicity, such as nausea and vomiting
"A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease (TRIUMPH-3) - Lilly Clinical Trials"
it is a crucial component of overall metabolic health and longevity
Direct and Metabolite Effects: While direct GLP-1R expression on -cells is low, degradation products of GLP-1, such as GLP-1(9-36) , may also inhibit glucagon secretion by activating inhibitory G proteins (Gi/o) and modulating calcium channels (Zheng et al., 2024)
Research shows that most people re-gain at least a portion of their weight back after discontinuing the medication