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Using both genetic and pharmacological inhibition, our work is consistent with these data in that linagliptin retained the ability to improve glucose tolerance in animals devoid of all Gcg peptides

Novel AOMs, largely based around incretin therapy, may exceed weight loss of 20% [10, 75], however, most trials evaluating their efficacy and safety were performed with younger adults, and those that include older adults often poorly define the number of participants in each age group

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