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rather, it induces an amino acid starvation response by upregulating the expression of SLC38A1, suggesting that SLC38A1 is a major importer of glutamine into these cells 90

L-arginine can interact with certain medications and cause adverse effects, especially in people with pre-existing medical conditions

The median maximum excess weight loss percentage (%EWLmax) was 47.5%, but the final median %EWL decreased to only 24.2% after long-term follow-up (up to 19 years)

One area of concern is its possible link to gastrointestinal issues, particularly acid reflux

What to expect: Systemic benefits like improved skin quality and reduced inflammation often appear within 48 weeks

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