A trial funded by Eli Lilly, the injected drug's maker, found that "in patients with obesity or overweight, withdrawing tirzepatide led to substantial regain of weight." On the other hand, continuing on with tirzepatide kept the weight off, over the full two years of the trial
This is in keeping with the known association between obesity and T2D and psychiatric illness
SID, steroid-induced diabetes
See more comments To view or add a comment, sign in More Relevant Posts An insightful commentary on Medscape today, What Beats the Biohacking Drug Metformin for Healthy Aging?, reinforces an important lesson: healthy aging is driven by comprehensive lifestyle interventions, not just medication

Physical health challenges include: Skin Infections and Irritation: Excess skin creates folds where moisture and bacteria accumulate Mobility Limitations: Loose skin can interfere with exercise and physical activities Hygiene Difficulties: Hard-to-clean skin folds increase infection risk Chronic Pain: Heavy, hanging skin can cause back and postural problems Psychological impacts often include: Body Image Disappointment: Feeling like your transformation is incomplete Clothing Fit Issues: Inability to properly showcase your new body shape Intimacy Concerns: Feeling self-conscious about loose skin Activity Avoidance: Reluctance to participate in beach activities or sports These challenges are particularly relevant in Miamis active, beach-focused lifestyle where form-fitting clothing and swimwear are part of daily life
However, the very description of the metabolic state using NMR may sometimes run into technical limits