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Additionally, GLP-1 signaling appears to influence stress response systems and emotional regulation, which are important factors in addiction vulnerability and relapse

Circulation 143 (21), e984e1010

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And you have a lot of sports that have high injury rates that are especially a lot of stuff that has impacts to the hands, martial arts and things like that, where probably the sport itself and its impact on training your bodys energy systems is positive, but just the injury rate is taking you out