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At time 0 min, mice were given orally either l-valine (1 g/kg, 20 uL/g), d-glucose (2 g/kg, 20 uL/g) or milliQ water (20 uL/g) mixed with acetaminophen (100 mg/kg)

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Lowering the insulin dosage, and adjustments in meal patterns or exercise may be needed

655 Omega-3 supplementation: In a single-arm, open-label trial of seal oil -3 PUFA supplementation (composed of eicosapentaenoic acid, docosapentaenoic acid, and docosahexaenoic acid) for 1 year in patients with T1DM and diabetic sensorimotor polyneuropathy, a 29% improvement in the primary endpoint of corneal nerve fiber length was observed