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Clinical trials show Zepbound leads to more weight loss than Wegovy, with participants losing up to 21% of body weight versus 15% on Wegovy, while generally experiencing fewer gastrointestinal side effects

This creates a natural feeling of fullness that lasts longer after meals

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As a GLP-1 receptor agonist, semaglutide slows down gastric emptying and alters digestive processes

The JAK-STAT pathway senses and transduces IFN-signals via a phosphorylation cascade to activate ISG expression (Figure 7A)