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Endometriosis is associated with an increased aromatase enzyme activity in granulosa cells, resulting in elevated follicular estradiol secretion (32)

To estimate NADPH concentration in the sample before freezing, calculated value is added to the NADPH concentration measured in frozen sample

Referral thresholds are broadly guided by NICE but may vary according to local NHS Integrated Care System (ICS) policies

Any references to GH, IGF-1, or pulse-related pathways are provided strictly for scientific context within laboratory research and do not imply therapeutic, diagnostic, or clinical use

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