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Additionally, patients on chemotherapy should consult with their oncologist prior to using glutathione, as it may interfere with the oxidative stress mechanisms that some chemotherapeutic agents rely on to exert their cytotoxic effects
Summary of Revisions: Standards of Medical Care in Diabetes2020
When glutathione neutralizes a free radical, it becomes temporarily depleted
However, a noticeable effect on weight loss and fat burning will probably take several days to several weeks, depending on the metabolism, age, health, and lifestyle