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In the SURMOUNT-4 trial, withdrawing tirzepatide after initial weight loss led to weight regain, while continued treatment maintained and extended weight reduction

Analysis of association between vitamin D deficiency and insulin resistance

Overall, Syn S129E exhibited promiscuous, nonfunctional interactions with a broad spectrum of proteins compared to the specific interactions observed for Syn WT

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Eligibility depends on eGFR and cardiovascular risk status