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J., Wu, Z., Chew, H
In addition, activation of GLP-1R regulates mitochondrial over fission by the cAMP/PKA pathway while improving mitochondrial function in A-treated astrocytes and ameliorating pathological lesions in AD (Xie et al., 2021)
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Het primaire eindpunt van de studie was de verandering in de cerebrale glucosemetabolische snelheid in de corticale gebieden van de hersenen (hippocampus, mediale temporale lob en posterieure cingulate cortex), wat niet werd behaald