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10.1046/j.1365-3156.1999.00387.x Trop

Adducts formed by the interaction of acetaldehyde with erythrocyte membranes may be associated with ethanol-induced macrocytosis, a condition characterized by unusually large numbers of enlarged erythrocytes in the blood

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First, siRNA-mediated suppression of the citrate/isocitrate transporter results in a reduction of citrate accumulation in the cytoplasm, concomitant with a modest reduction of GSIS in INS-1 832/13 cells and in isolated rat islets [61]