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Rahimzadeh A, Mirakabad FS, Movassaghpour A, et al

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Niacinamide can occasionally cause a mild flushing sensation at the injection site, which is harmless and temporary

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Hypoxia and inflammation activate p53 via phosphorylation

To further determine the importance of the PI3K/AKT signaling in NAC-modulated function, TSPCs were treated with, or without, NAC in the presence or absence of an PI3K/AKT inhibitor (LY294002), and the relative levels of PI3K/AKT phosphorylation and integrin 51 expression were analyzed by Western blotting