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The structure of the IRAP (Mpakali et al., 2020) was found very similar to that reported previously with a phosphinic pseudotripeptide transition-state analogue binding to the enzyme, vide infra (Mpakali et al., 2017)

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The present review attempts to summarize the traditional plants of Western Himalaya that are used to cure the GI disorders and also highlights the significance phytoconstituents on GI disorders