Oral and some research doses use micrograms
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Nuclear factor erythroid 2-related factor 2 (Nrf2) as the key transcription factor playing an essential role in redox balance and depleted in COPD patients (Deshmukh et al., 2017), modulates the expression of approximately 100 genes functioning the state of redox, inducing the transcription of glutathione (GSH) (Osburn et al., 2006)
However, human clinical trials remain scarce
Crone EA, Donohue SE, Honomichl R, Wendelken C, Bunge SA (2006)
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