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Tirzepatide, being approved, additionally carries a labeled boxed warning for thyroid C-cell tumors based on rodent studies
Larger, randomized controlled trials with extended follow-up periods are needed to establish definitive guidelines for the use of arGLP-1 in post-bariatric care
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Individual responses vary based on baseline blood pressure, initial weight, and genetic factors that influence cardiovascular sensitivity to GLP-1 activation
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