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However, observational studies suggest that whilst acute toxicity remains exceptionally rare, sustained very high levels of B12particularly from supplements or injectionsmay be associated with certain health concerns, though these are correlations rather than proven causal relationships
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[DOI] [PMC free article] [PubMed] [Google Scholar] 103.Cheng Y., Chen Z., Liao T., Lin C., Shen C.-H., Wang Y., Chang C., Liu R., Chen R.P., Tu P
Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice
113115, 10.1016/j.mad.2003.11.005
If your B12 levels are already solid, the impact might be minimal
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