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A large observational analysis published in JAMA Psychiatry examined data from adults with alcohol use disorder and found that semaglutide reduced alcohol consumption compared to placebo, with researchers attributing the effect to the same dopaminergic dampening that appears to reduce food noise

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Strategies could include dosing rapid-acting insulins 30-minutes after the start of eating (instead of the typical 15 minutes before meals), or split-bolus dosing, whereby a patient takes 50% of their rapid acting insulin before a meal, and 50% 30-minutes after the start of a meal

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