It can push stem or progenitor cells towards repair phenotypes and it advances regeneration-specific cell cycle genes
10.1016/j.cell.2010.07.041 280
Link between type 2 diabetes and Alzheimers disease: from epidemiology to mechanism and treatment
Schizophrenia is a debilitating and severe mental illness that affects approximately 1% of the general population worldwide.2 Schizophrenia is characterized by positive, negative, and cognitive symptoms with poor insight and impaired psychosocial function.3 Although acute psychosis is controlled with pharmacotherapy, negative and cognitive symptoms tend to be unresponsive to pharmacotherapy.456 In addition, most second-generation antipsychotics (SGA) except clozapine have been shown to have no significant advantages over first-generation antipsychotics (FGA) even in the domain of negative and cog-nitive symptoms.7 The chronicity and deterioration of the illness raise the possibility that schizophrenia may have neurodegenerative aspects
SP preferentially binds to NK1R and NK1R is expressed in many of the same brain regions as SP (Mantyh et al., 1984
Wolters M, Hermann S, Golf S, Katz N, Hahn A
