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Some researchers combine AOD 9604 with extended fasting protocols

upregulates GH receptor expression in fibroblasts to amplify downstream healing signals

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Inhibitors of GH signal transduction pathways (post-receptor) Given that GH activates JAK-STAT, PI3K/AKT/mTOR and MAPK signaling, agents which target components of these signaling pathways would be expected to modulate pathway-specific GH effects

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