TREM2 agonists, such as AL002, promote microglial transformation toward the anti-inflammatory M2 phenotype, thereby reducing the release of pro-inflammatory M1 cytokines (e.g., TNF-, IL-1) and indirectly mitigating inflammation-driven ferroptotic cascades
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Brain Res 724(1):121124 Shapiro RE, Miselis RR (1985) The central neural connections of the area postrema of the rat
Implanted epidural/subdural electrode strips targeting the cortical SCAN nodes may also have critical roles, either by recording control signals or delivering direct cortical stimulation 28,97
Crawford, E.D