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Higher doses of semaglutide (2.4 mg weekly) produced striking results in clinical trials, with participants losing 1015% of body weight on average

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Some people, particularly those still in the titration phase or those sensitive to gastrointestinal effects, report mild increases in nausea

This is the first randomized, placebo-controlled clinical trial of semaglutide designed to study the phenomenon, said Christian Hendershot, first author of the study and director of clinical research at USCs Institute for Addiction Science

Despite ongoing research, both medications offer promising solutions for managing type 2 diabetes and weight loss challenges

Researchers are exploring new formulations and combinations that could offer even greater benefits with fewer side effects