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We noted in the CY 2026 OPPS/ASC proposed rule that based on the description the applicant provided, the Axoguard HA+ Nerve Protector TM is a porcine SIS ECM with hyaluronate-alginate coating used for the management and protection of peripheral nerve injuries where there is no gap or following closure of a gap, and thus, could be encompassed by the descriptors C1763 and C1765

Neurological Function : B12 helps maintain the myelin sheath that protects nerves and enables proper signalling between brain and body

Riboflavin (B2) The water-soluble riboflavin plays a role in the metabolizing of carbohydrates, protein, and fat

Excessive NAM depletion directly reduces the substrate supply for NAD+ synthesis, leading to decreased intracellular NAD+ levels

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