sglt2 and glp 1 together Frontiers Illustration of potential synergistic effects

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Both groups had a mean follow-up of 57 months with differences in survival at 5 years (11% in the LVRS group and 5% in the control group, P=0.001), showing lobectomy to be a safe technique, even in patients with more severe and higher-risk emphysema

However, since the signalling pathway is complicated and bidirectional, application of BDNF in neuroprotection in humans remains to be elucidated

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