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Metabolic disorders Insulin resistance and diabetes Type 2 diabetes mellitus, metabolically associated fatty liver disease, neurodegenerative diseases, and cardiovascular diseases are significantly increased by insulin resistance

Low plasma ghrelin is associated with insulin resistance, hypertension, and the prevalence of type 2 diabetes

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However, unlike arsenic trioxide, GSAO (Dilda et al., 2005b) or PENAO (Dilda et al., 2009), Darinaparsin activity is unaffected by the expression of ABCC1 (MRP-1), modulation of GSH levels (Diaz et al., 2008) and heme-oxygenase inhibition (Garnier et al., 2013)

Therefore, balanced nutrition is essential for maintaining metabolic health