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Understanding this timeline prevents premature discouragement
Unlike Wegovy, compounded semaglutide does not go through the same rigorous FDA approval process as commercially available medications
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all were exposed to systemic glucocorticoids, and N=1165 (41%) developed new or worsening hyperglycaemia in those who had diabetes at baseline
Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, Colagiuri S, Guariguata L, Motala AA, Ogurtsova K, et al: Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9(th) edition
Common scenarios include achieving target weight loss goals, experiencing intolerable adverse effects such as persistent nausea or gastrointestinal disturbances, financial constraints related to medication costs, pregnancy planning or confirmation (tirzepatide should be discontinued when pregnancy is recognized), or development of contraindications
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