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First, we emulated the two cardiovascular outcome trials SUSTAIN-6 (semaglutide versus placebo) and SURPASS-CVOT (tirzepatide versus dulaglutide) using the RCT-DUPLICATE approach to benchmark findings and inform the study design and analytic approach for expanded questions

Studies have shown that certain medications like Ozempic called GLP-1 agonists can help with weight loss

While COPD isnt reversible, it is preventable (a major way to help prevent it is to not smoke) and treatable

(2021, NEJM) reported the dose-response pharmacology that established tirzepatide as a distinct compound from the single-receptor class

But science is evolving and self-correcting

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