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Half-life and body duration comparison Semaglutide has the longest half-life at approximately 7 days, making it the slowest to clear from your system

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Weight Loss Results at 48 Weeks: Key Percentage Findings At 48 weeks, the 12 mg retatrutide dose produced a mean body weight reduction of approximately 24.2%, compared with approximately 2.1% in the placebo group, with weight loss still ongoing at trial end