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From a pragmatic point of view, a successful weight loss drug that doesnt require you to diet and exercise probably isnt great for all the guilt sign ups powering PLNTs ability to make a buck (although I fully support people changing their diet and exercise, there is the question of if they were going to do that they wouldnt have needed the drug in the first place...)

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Fatigue is common in the first weeks, often related to reduced caloric intake as appetite suppression takes effect

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Your doctor can recommend what pain medication to take with Contrave