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With each cellular division, telomeres shorten slightly and telomere shortening is the main cause of age-related breakdown of cells.65,66 In 2009, the Nobel Prize in Physiology or Medicine was awarded to three scientists for the discovery of how our chromosomes and DNA are protected by telomeres and the enzyme telomerase.67 Telomerase is an enzyme that can place additional DNA repeat sections on the ends of telomeres

Free Radical Biol Med 49:161728 Yang Y, Sharma R, Sharma A, Awasthi S, Awasthi YC (2003) Lipid peroxidation and cell cycle signaling: 4-hydroxynonenal, a key molecule in stress mediated signaling

* Correspondence: Ayodeji Mathias Adegoke, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

PA requests for non-preferred immunomodulators, atopic dermatitis drugs must be completed, signed, and dated by the prescriber